A Case of Rhino-Orbital-Cerebral Mucormycosis Successfully Treated by Surgical Treatment and Posaconazole / 대한의진균학회지
Korean Journal of Medical Mycology
;
: 14-19, 2016.
Artigo
em Coreano
| WPRIM
| ID: wpr-76121
ABSTRACT
Mucormycosis is a highly aggressive and fatal fungal infection. Due to its rapid progression, combination of early wide surgical debridement with administration of antifungal agent is extremely crucial. European Society for Clinical Microbiology and Infectious Diseases, and European Confedration of Medical Mycology recommended amphotericin B as the first-line of treatment and posaconazole as the salvage agent for mucormycosis. We report a case of rhino-orbital-cerebral mucormycosis successfully treated by changing antifungal agent from the first-line amphotericin B to the salvage agent posaconazole. A 57-years-old female with uncontrolled type 2 diabetes mellitus was presented with foot abscess and rhino-orbital-cerebral mucormycosis. The infection was intractable despite orbital orbital exenteration with surgical debridement and 2 months of antibiotics treatment including amphotericin B. Changing amphotericin B to posaconazole resulted in clinical improvement within the first week. Conclusively the newly administered antifungal agent, posaconazole is expected to be an effective salvage treatment option for mucormycosis after failure of initial treatment of amphotericin B with surgical management.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Órbita
/
Anfotericina B
/
Doenças Transmissíveis
/
Desbridamento
/
Diabetes Mellitus Tipo 2
/
Abscesso
/
Pé
/
Antibacterianos
/
Mucormicose
/
Micologia
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medical Mycology
Ano de publicação:
2016
Tipo de documento:
Artigo
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