Experiemental Model for Ménière's Disease Using Surgical Ablation of Endolymphatic Sac / 대한평형의학회지
Journal of the Korean Balance Society
;
: 95-100, 2016.
Artigo
em Coreano
| WPRIM
| ID: wpr-761228
ABSTRACT
Endolymphatic hydrops is a representing pathologic finding of Ménière's disease. For the induction of endolymphatic hydrops in an animal model, surgical ablation of endolymphatic sac has been used. Although traditional model with the blockage of endolymphatic sac induced severe hydrops, it has several limitations for the study of pathophysiology of Ménière's disease. Recently, modified experimental models have been introduced, in which additional procedure was performed to induce the acute aggravation of hydrops after the surgical ablation. These new models could be helpful to elucidate the mechanism and develop a new treatment of Ménière's disease. In this review, we introduce the characteristics of animal models using surgical ablation of endolymphatic sac from the classical model to novel modified models.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Saco Endolinfático
/
Hidropisia Endolinfática
/
Modelos Animais
/
Edema
/
Doença de Meniere
/
Modelos Teóricos
Tipo de estudo:
Estudo prognóstico
Idioma:
Coreano
Revista:
Journal of the Korean Balance Society
Ano de publicação:
2016
Tipo de documento:
Artigo
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