Natural History and Treatment Indications of Chronic Hepatitis B / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 245-250, 2019.
Article
em Ko
| WPRIM
| ID: wpr-761570
Biblioteca responsável:
WPRO
ABSTRACT
HBV is the most common etiology of both liver cirrhosis and hepatocellular carcinoma in Korea. Despite much progress made, the currently available antiviral therapies cannot eradicate or eliminate this virus. Hence, the benefits and risks of antiviral therapy should be carefully evaluated on an individual basis and within the context of the clinical situation. The ultimate goals of treatment are to decrease the mortality from liver disease. The benefits of antiviral therapy come from prevention of progression of liver disease. Understanding the natural history of chronic HBV infection is a key step in the decision making process to treat patients with chronic HBV infection. Generally, chronic hepatitis B patients in the immune tolerant phase and immune inactive phase are not recommended to undergo antiviral treatment, except for those patients in special conditions (e.g., immunosuppression or anticancer chemotherapy). Chronic hepatitis B patients in the immune active phase are recommended for antiviral therapy. For patients with liver cirrhosis, treatment should be considered when serum HBV DNA is detectable regardless of the serum level of ALT.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
DNA
/
Vírus da Hepatite B
/
Mortalidade
/
Terapia de Imunossupressão
/
Carcinoma Hepatocelular
/
Medição de Risco
/
História Natural
/
Hepatite B Crônica
/
Tomada de Decisões
/
Hepatite Crônica
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2019
Tipo de documento:
Article