Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study
Allergy, Asthma & Immunology Research
;
: 723-735, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-762151
ABSTRACT
PURPOSE:
To investigate the causative allergens and clinical characteristics of Korean adult patients with food allergy (FA).METHODS:
This retrospective, cross-sectional single-institutional study enrolled Korean adult patients (n = 812) suspected of having FA. For diagnosis, causality assessment history taking, ImmunoCAP specific immunoglobulin E measurement and/or skin prick test were performed.RESULTS:
Among 812 patients, 415 were diagnosed as having FA. The most common causative allergen was fruit, with a diagnosis of pollen food allergy syndrome (PFAS 155, 37.3%), followed by crustaceans (111, 26.7%), wheat (63, 15.1%), fruits in patients without PFAS(43, 10.3%), buckwheat (31, 7.4%), peanut (31, 7.4%), walnut (25, 6.0%), red meat due to reaction to galactose-α-1,3-galactose (α-Gal) (8, 1.9%), and silkworm pupa (13, 3.1%). Allergy to egg, milk, fish, or shellfish was rare in Korean adults. One-third of patients with FA exhibited multiple FAs (238/415, 57.3%); the average number of causative allergens was 2.39. About 129 patients (31.0%) were diagnosed as having anaphylaxis; in these patients, wheat was the most frequent causative food. Twenty patients were further diagnosed with food-dependent exercise-induced anaphylaxis (FDEIA); all were due to wheat. In particular, crustaceans, wheat, PFAS, buckwheat, and red meat (α-Gal) were also frequent causes of anaphylaxis.CONCLUSIONS:
Wheat, fruits with or without PFAS, and crustaceans are important and frequent causative allergens in Korean adult FA; these allergens differ from those found in childhood FA. It is notable that non-classic allergies, such as PFAS, FDEIA, and α-Gal allergy, are the important causes of anaphylaxis in Korean adult FA.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Óvulo
/
Arachis
/
Pólen
/
Pupa
/
Frutos do Mar
/
Bombyx
/
Pele
/
Triticum
/
Imunoglobulina E
/
Imunoglobulinas
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo de prevalência
Limite:
Adulto
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Allergy, Asthma & Immunology Research
Ano de publicação:
2019
Tipo de documento:
Artigo
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