Syringocystadenocarcinoma Papilliferum: A Case Report and Review of the Literature
Annals of Dermatology
;
: 559-562, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-762372
ABSTRACT
Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant adnexal neoplasm, which is considered as a malignant counterpart of syringocystadenoma papilliferum (SCAP). Clinically, SCACP appears as a nodule, inflammatory plaque, or tumor. The lesion is usually covered with crusts, which are formed by secretion of the apocrine epithelial cells. Histologically, SCACP resembles SCAP, with cystic papillomatous invaginations connected to the skin surface by funnel-shaped structures lined by infundibular epithelium. The stroma of the tumor consists of a dense inflammatory infiltrate of plasma cells and lymphocytes. SCACP differs from SCAP in terms of the architectural and cytological features of the tumor cells, and is characterized by higher nuclear cytoplasmic ratio, nuclear irregularity, coarse chromatin, and increased mitotic activity. However, the immunohistochemical findings of SCACP vary. Since only 49 cases of SCACP have been reported in the English literature, the clinical and histologic characteristics of SCACP have not been fully established. Further studies on the diagnostic criteria for SCACP are warranted. Here, we report a rare case of SCACP and present a review of other relevant literature.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plasmócitos
/
Pele
/
Neoplasias das Glândulas Sudoríparas
/
Cromatina
/
Linfócitos
/
Citoplasma
/
Células Epiteliais
/
Epitélio
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2019
Tipo de documento:
Artigo
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