A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection
Annals of Pediatric Endocrinology & Metabolism
;
: 68-70, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-762586
ABSTRACT
Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%–20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immunemediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Poliúria
/
Rubéola (Sarampo Alemão)
/
Autoanticorpos
/
Trombocitopenia
/
Micção
/
Catarata
/
Redução de Peso
/
Diabetes Mellitus
/
Diabetes Mellitus Tipo 1
/
Permeabilidade do Canal Arterial
Limite:
Adolescente
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Annals of Pediatric Endocrinology & Metabolism
Ano de publicação:
2019
Tipo de documento:
Artigo
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