Association between Change in Alcohol Consumption and Metabolic Syndrome: Analysis from the Health Examinees Study
Diabetes & Metabolism Journal
;
: 615-626, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-763684
ABSTRACT
BACKGROUND:
The association between change in alcohol intake and metabolic syndrome is unclear.METHODS:
This retrospective cohort consisted of 41,368 males and females from the Health Examinees-GEM study. Participants were divided into non-drinkers (0.0 g/day), light drinkers (male 0.1 to 19.9 g/day; female 0.1 to 9.9 g/day), moderate drinkers (male 20.0 to 39.9 g/day; female 10.0 to 19.9 g/day), and heavy drinkers (male ≥40.0 g/day; female ≥20.0 g/day) for each of the initial and follow-up health examinations. Logistic regression analysis was used to determine the adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for developing metabolic syndrome according to the change in alcohol consumption between the initial and follow-up health examinations. Adjusted mean values for the change in waist circumference, fasting serum glucose (FSG), blood pressure, triglycerides, and high density lipoprotein cholesterol (HDL-C) levels were determined according to the change in alcohol consumption by linear regression analysis.RESULTS:
Compared to persistent light drinkers, those who increased alcohol intake to heavy levels had elevated risk of metabolic syndrome (aOR, 1.45; 95% CI, 1.09 to 1.92). In contrast, heavy drinkers who became light drinkers had reduced risk of metabolic syndrome (aOR, 0.61; 95% CI, 0.44 to 0.84) compared to persistent heavy drinkers. Increased alcohol consumption was associated with elevated adjusted mean values for waist circumference, FSG, blood pressure, triglycerides, and HDL-C levels (all P<0.05). Reduction in alcohol intake was associated with decreased waist circumference, FSG, blood pressure, triglycerides, and HDL-C levels among initial heavy drinkers (all P<0.05).CONCLUSION:
Heavy drinkers who reduce alcohol consumption could benefit from reduced risk of metabolic syndrome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Triglicerídeos
/
Glicemia
/
Pressão Sanguínea
/
Consumo de Bebidas Alcoólicas
/
Modelos Lineares
/
Modelos Logísticos
/
Razão de Chances
/
Estudos Retrospectivos
/
Estudos de Coortes
/
Seguimentos
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Diabetes & Metabolism Journal
Ano de publicação:
2019
Tipo de documento:
Artigo
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