Avidity of serum immunoglobulin G antibodies to Porphyromonas gingivalis in the elderly with chronic periodontitis
International Journal of Oral Biology
;
: 14-19, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-764033
ABSTRACT
The present study aimed at evaluating serum immunoglobulin G (IgG) avidity to Porphyromonas gingivalis in elderly patients with mild and severe chronic periodontitis. The avidity of antibodies against P. gingivalis present in the sera of 18 patients with mild chronic periodontitis and 18 patients with severe chronic periodontitis was evaluated using an ammonium thiocyanate-dissociated enzyme-linked immunosorbent assay (ELISA). The results showed that the mean absorbance value in serum IgG antibody titers was significantly higher in the severe chronic periodontitis group than in the mild chronic periodontitis group (198 ± 35 ELISA unit [EU] vs. 142 ± 32 EU, p < 0.01). However, there was no significant difference between the two groups in antibody avidity (65 ± 57 EU vs. 54 ± 27 EU). These findings suggest that humoral immune responses to P. gingivalis between mild and severe chronic periodontitis in elderly patients are characterized by the differences in the quantity rather than the quality of the antibodies.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Imunoglobulina G
/
Imunoglobulinas
/
Ensaio de Imunoadsorção Enzimática
/
Porphyromonas
/
Porphyromonas gingivalis
/
Periodontite Crônica
/
Imunidade Humoral
/
Compostos de Amônio
/
Geriatria
/
Anticorpos
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
International Journal of Oral Biology
Ano de publicação:
2019
Tipo de documento:
Artigo
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