Trifolium pratense induces apoptosis through caspase pathway in FaDu human hypopharynx squamous carcinoma cells
International Journal of Oral Biology
;
: 81-88, 2019.
Artigo
em Coreano
| WPRIM
| ID: wpr-764047
ABSTRACT
Trifolium pratense leaves (red clover) has been used in Oriental and European folk medicine for the treatment of whooping cough, asthma, and eczema, and is now being used to treat and alleviate the symptoms, such as hot flushes, cardiovascular health effects that occur in postmenopausal women. However, relatively little scientific data is available on the physiological activity of this plant. Therefore, in this study, we investigated the anti-cancer activity of T. pratense leaves using methanol extract of T. pratense leaves (MeTP) on human FaDu hypopharyngeal squamous carcinoma cells. MeTP inhibited the viability of FaDu cells by inducing apoptosis through the cleavage of procaspase-3,
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plantas
/
Asma
/
Neoplasias Bucais
/
Carcinoma de Células Escamosas
/
Regulação para Baixo
/
Regulação para Cima
/
Coqueluche
/
Western Blotting
/
Apoptose
/
Trifolium
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
International Journal of Oral Biology
Ano de publicação:
2019
Tipo de documento:
Artigo
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