Human Epidermal Growth Factor Receptor 2-positive Mucinous Carcinoma with Signet Ring Cell Differentiation, Which Showed Complete Response after Neoadjuvant Chemotherapy / 한국유방암학회지
Journal of Breast Cancer
;
: 336-340, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-764258
ABSTRACT
Mucinous carcinoma (MC) is a rare subtype of breast cancer, which is composed of tumor cells floating in the abundant extracellular mucin. This form of cancer is usually estrogen receptor/progesterone receptor positive and human epidermal growth factor receptor 2 (HER2) negative. Here, we present a case of HER2-positive MC with an unusual signet ring cell differentiation. It is very rare that a breast tumor consists entirely of signet ring cells. The tumor showed pathologic complete response (pCR) after neoadjuvant chemotherapy with trastuzumab and pertuzumab. pCR of HER2-positive MC has rarely been described in literature. It is important to consider the biological heterogeneity of MCs for effective management.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Características da População
/
Neoplasias da Mama
/
Diferenciação Celular
/
Reação em Cadeia da Polimerase
/
Carcinoma de Células em Anel de Sinete
/
Adenocarcinoma Mucinoso
/
Receptor ErbB-2
/
Terapia Neoadjuvante
/
Tratamento Farmacológico
/
Fator de Crescimento Epidérmico
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Breast Cancer
Ano de publicação:
2019
Tipo de documento:
Artigo
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