Evaluation of Point-of-Care Testing for C-Reactive Protein in Forensic Medicine
Journal of Korean Medical Science
;
: e246-2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-765085
ABSTRACT
BACKGROUND:
C-reactive protein (CRP) is an acute-phase protein whose level increases in response to tissue injury, infection, or other inflammation. It is used in clinical and forensic settings. Point-of-care (POC) testing has recently become available, and it is considered to be useful during postmortem examinations. However, laboratory testing of postmortem blood samples is difficult due to hemolysis and postmortem clotting.METHODS:
The utility of POC testing for CRP during postmortem examination was evaluated using cardiac blood from the inferior vena cava. The whole blood sample was immediately tested using the POC instrument. Subsequently, the same sample was processed to obtain the serum, which was tested using common laboratory instruments.RESULTS:
The postmortem POC test had a high positive predictive value and specificity, and the results strongly correlated with the laboratory test results.CONCLUSION:
POC CRP testing is valid in postmortem examination and can be used in forensic medicine (postmortem inspection and autopsy).
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Autopsia
/
Veia Cava Inferior
/
Proteína C-Reativa
/
Proteínas de Fase Aguda
/
Sensibilidade e Especificidade
/
Sistemas Automatizados de Assistência Junto ao Leito
/
Ciências Forenses
/
Testes Imediatos
/
Medicina Legal
/
Hemólise
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2019
Tipo de documento:
Artigo
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