Effect of Phacoemulsification on Intraocular Pressure in Healthy Subjects and Glaucoma Patients
Journal of Korean Medical Science
;
: e47-2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-765151
ABSTRACT
BACKGROUND:
We investigated how cataract surgery might influence long-term intraocular pressure (IOP) change in both healthy subjects and glaucoma patients.METHODS:
A retrospective analysis of patients who had had clear corneal phacoemulsification with a minimum of 12 months of follow up was performed. Glaucoma patients with medically controlled open-angle glaucoma and healthy subjects with no glaucoma were included in the analysis. The change of IOP after phacoemulsification and factors associated with postoperative IOP change were investigated.RESULTS:
In total, 754 eyes of 754 patients, specifically 106 patients with glaucoma and 648 patients with no glaucoma (i.e., healthy subjects) were enrolled. The phacoemulsification effected a reduction of IOP 1.03 ± 3.72 mmHg in healthy subjects and 1.08 ± 3.79 mmHg in glaucoma patients at postoperative 1 year (P = 0.656). There were negative coefficients of IOP until 1 year of follow up (all P < 0.001), but the IOP change gradually showed a less steeply decreasing slope (correlation coefficient −0.993), compared with those for 1 week and 1 month of follow up (correlation coefficients −1.893 and −1.540, respectively). In the multivariate analysis, age and preoperative IOP showed significant associations with postoperative IOP change (regression coefficients −0.034 and 0.419 respectively, all P < 0.001).CONCLUSION:
Phacoemulsification resulted in IOP reduction, which effect regressed in healthy subjects and glaucoma patients over the course of long-term follow up. Therefore, long-term monitoring of IOP change is needed. In cases of higher preoperative IOP and young patients, phacoemulsification alone is a reliable option for IOP control.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Catarata
/
Glaucoma
/
Glaucoma de Ângulo Aberto
/
Análise Multivariada
/
Estudos Retrospectivos
/
Seguimentos
/
Facoemulsificação
/
Voluntários Saudáveis
/
Pressão Intraocular
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2019
Tipo de documento:
Artigo
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