Cold Allodynia after C2 Root Resection in Sprague-Dawley Rats
Journal of Korean Neurosurgical Society
;
: 186-193, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-765245
ABSTRACT
OBJECTIVE:
The purpose of this study was to evaluate pain-related behaviors after bilateral C2 root resection and change in pain patterns in the suboccipital region in rats.METHODS:
Male Sprague-Dawley rats were randomly assigned to three groups (n=25/group); näive, sham, and C2 resection. Three, 7, 10, and 14 days after surgery, cold allodynia was assessed using 20 μL of 99.7% acetone. c-Fos and c-Jun were immunohistochemically stained to evaluate activation of dorsal horn gray matter in C2 segments of the spinal cord 2 hours, 1 day, 7 days, and 14 days after surgery.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Acetona
/
Medula Espinal
/
Ratos Sprague-Dawley
/
Substância Cinzenta
/
Corno Dorsal da Medula Espinal
/
Hiperalgesia
/
Neuralgia
/
Neurônios
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Journal of Korean Neurosurgical Society
Ano de publicação:
2018
Tipo de documento:
Artigo
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