The ‘Hot Cross Bun’ Sign Is Not Always Multiple System Atrophy: Etiologies of 11 Cases
Journal of Movement Disorders
;
: 27-30, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-765840
ABSTRACT
OBJECTIVE:
To clarify the specificity of the ‘hot cross bun’ sign (HCBS) for multiple system atrophy (MSA) in adult cerebellar ataxia or parkinsonism.METHODS:
The radiologic information systems at an academic center and affiliated veterans' hospital were queried using the keywords ‘hot cross bun,’ ‘pontocerebellar,’ ‘cruciate,’ ‘cruciform,’ ‘MSA,’ ‘multiple system atrophy,’ and ‘multisystem atrophy.’ Scans were reviewed by a neurologist and neuroradiologist to identify the HCBS. Subjects with the HCBS were reviewed by 2 neurologists to identify the most likely etiology of the patient's neurologic symptoms.RESULTS:
Eleven cases were identified. Etiologies included MSA (4 probable, 2 possible), hereditary cerebellar ataxia (3/11), probable dementia with Lewy bodies (1/11), and uncertain despite autopsy (1/11).CONCLUSION:
MSA was the most common etiology. However, 5 of the 11 patients did not have MSA. The most common alternate etiology was an undefined hereditary cerebellar ataxia (3/11).
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Autopsia
/
Atrofias Olivopontocerebelares
/
Imageamento por Ressonância Magnética
/
Ataxia Cerebelar
/
Sensibilidade e Especificidade
/
Sistemas de Informação em Radiologia
/
Corpos de Lewy
/
Atrofia de Múltiplos Sistemas
/
Transtornos Parkinsonianos
/
Demência
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo prognóstico
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Journal of Movement Disorders
Ano de publicação:
2019
Tipo de documento:
Artigo
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