Hashimoto's Encephalopathy with Reversible Diffuse Leukoencephalopathy
Journal of Neurocritical Care
;
(2): 54-57, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-765894
ABSTRACT
BACKGROUND:
The magnetic resonance imaging (MRI) findings of Hashimoto's encephalopathy (HE) are variable; images range from having a normal appearance, to showing ischemic lesions, demyelination, or vasogenic edema. CASE REPORT A 57-year-old woman presented with a sudden onset of dysarthria and dizziness. Routine blood tests were normal and the MRI was unremarkable. After admission, she developed aphasic seizures and myoclonus, and eventually became comatose. A follow up MRI showed diffuse high signal intensities at the bilateral cerebral white matter on fluid attenuated inversion recovery imaging. The serum titers of the anti-thyroglobulin antibody and anti-thyroperoxidase antibody were increased. After 5 days of 1,000 mg/day of intravenous methylprednisolone infusion, she recovered rapidly.CONCLUSION:
We propose that repeated brain MRIs are necessary for the diagnosis of HE. Diffuse leukoencephalopathy may be a pathologic finding on MRI and, in this case study, was shown to be reversible after applying an appropriate treatment.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Convulsões
/
Encéfalo
/
Encefalopatias
/
Metilprednisolona
/
Imageamento por Ressonância Magnética
/
Seguimentos
/
Doenças Desmielinizantes
/
Coma
/
Diagnóstico
/
Tontura
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Neurocritical Care
Ano de publicação:
2018
Tipo de documento:
Artigo
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