The Relationship Between Serum Total Bilirubin and Framingham Risk Score in Healthy Korean Men
Korean Journal of Health Promotion
;
: 1-7, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-771028
ABSTRACT
BACKGROUND:
Serum total bilirubin has been considered a harmful substance inducing oxidative reaction; but recently, there have been reports of it possessing antioxidative, anti-inflammatory and protective features against cardiovascular diseases. The purpose of this study was to investigate the relationship between total bilirubin and the Framingham risk score.METHODS:
This study involved 3,414 healthy Korean men who underwent a medical check-up in a health promotion center in 2008. We calculated the Framingham risk score using age, smoking status, systolic blood pressure, total cholesterol and high-density lipoprotein cholesterol.RESULTS:
The mean age of the participants was 44.9+/-8.8 years. The log transformed serum total bilirubin level and the Framingham risk score had a negative linear relationship in a simple linear regression analysis (R2 0.018, P<0.001). In a multivariable analysis model, as well, the log transformed serum total bilirubin level and the Framingham risk score had a negative linear relationship (R2 0.384, P<0.001).CONCLUSIONS:
Our study showed a statistically significant negative relationship between total bilirubin and the Framingham risk score. Total bilirubin had a stronger relationship with the Framingham risk score than other standard cardiovascular risk factors except smoking, and thus may be useful in predicting cardiovascular risk in the outpatient clinic.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fumaça
/
Bilirrubina
/
Pressão Sanguínea
/
Doenças Cardiovasculares
/
Fumar
/
Modelos Lineares
/
Colesterol
/
Fatores de Risco
/
Instituições de Assistência Ambulatorial
/
Promoção da Saúde
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Korean Journal of Health Promotion
Ano de publicação:
2013
Tipo de documento:
Artigo
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