Recent advances in cell sheet technology for bone and cartilage regeneration: from preparation to application / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 17-17, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-772267
ABSTRACT
Bone defects caused by trauma, tumour resection, infection and congenital deformities, together with articular cartilage defects and cartilage-subchondral bone complex defects caused by trauma and degenerative diseases, remain great challenges for clinicians. Novel strategies utilising cell sheet technology to enhance bone and cartilage regeneration are being developed. The cell sheet technology has shown great clinical potential in regenerative medicine due to its effective preservation of cell-cell connections and extracellular matrix and its scaffold-free nature. This review will first introduce several widely used cell sheet preparation systems, including traditional approaches and recent improvements, as well as their advantages and shortcomings. Recent advances in utilising cell sheet technology to regenerate bone or cartilage defects and bone-cartilage complex defects will be reviewed. The key challenges and future research directions for the application of cell sheet technology in bone and cartilage regeneration will also be discussed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Regeneração
/
Osso e Ossos
/
Regeneração Óssea
/
Cartilagem Articular
/
Engenharia Tecidual
/
Alicerces Teciduais
Idioma:
Inglês
Revista:
International Journal of Oral Science
Ano de publicação:
2019
Tipo de documento:
Artigo
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