Effect of histone acetylation on osteogenic differentiation of periodontal ligament stem cells derived from periodontitis tissue / 华西口腔医学杂志

ABSTRACT

Epigenetics is defined as a change in gene expression without the alteration of the genetic sequence. Such a change would be inherited by offspring. Histone acetylation is a type of epigenetics. Existing studies proposed that chronic periodontitis is related to epigenetic modification. In this review, we summarised the influence of chronic periodontitis on periodontal ligament stem cells by histone acetylation.