Genome Writing: Current Progress and Related Applications / 基因组蛋白质组与生物信息学报·英文版
Genomics, Proteomics & Bioinformatics
;
(4): 10-16, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-773007
ABSTRACT
The ultimate goal of synthetic biology is to build customized cells or organisms to meet specific industrial or medical needs. The most important part of the customized cell is a synthetic genome. Advanced genomic writing technologies are required to build such an artificial genome. Recently, the partially-completed synthetic yeast genome project represents a milestone in this field. In this mini review, we briefly introduce the techniques for de novo genome synthesis and genome editing. Furthermore, we summarize recent research progresses and highlight several applications in the synthetic genome field. Finally, we discuss current challenges and future prospects.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Engenharia Genética
/
Genoma Humano
/
Sequenciamento de Nucleotídeos em Larga Escala
/
Sistemas CRISPR-Cas
/
Edição de Genes
/
Métodos
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Genomics, Proteomics & Bioinformatics
Ano de publicação:
2018
Tipo de documento:
Artigo
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