Levels of blood free carnitine in preterm infants with different gestational ages and birth weights / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 562-566, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-774033
ABSTRACT
OBJECTIVE@#To examine blood concentrations of free carnitine (FC) in preterm infants with different gestational ages (GA) and birth weights (BW).@*METHODS@#A total of 3 368 preterm infants were enrolled as subjects. According to GA, they were divided into extremely preterm birth (EPTB) group (GA <28 weeks; n=39), very preterm birth (VPTB) group (28 ≤GA <32 weeks; n=405), moderately preterm birth (MPTB) group (32 ≤GA <34 weeks; n=507), and late preterm birth (LPTB) group (34 ≤GA <37 weeks; n=2 417); according to BW, they were divided into extremely low birth weight (ELBW) group (BW <1 000 g; n=36), very low birth weight (VLBW) group (1 000 g ≤BW <1 500 g; n=387), low birth weight (LBW) group (1 500 g ≤BW <2 500 g; n=1 873), and normal birth weight (NBW) group (2 500 g ≤ BW <4 000 g; n=1 072). Blood concentrations of FC were measured between 72 hours and 7 days after birth.@*RESULTS@#The EPTB and VPTB groups had significantly higher FC concentrations than the MPTB and LPTB groups (P<0.05), and the MPTB group had significantly higher FC concentrations than the LPTB group (P<0.05). The lower limit of the 95% medical reference range of FC increased with the reduction in GA. The ELBW and VLBW groups had significantly higher FC concentrations than the LBW and NBW groups (P<0.05). The LBW group had significantly higher FC concentrations than the NBW group (P<0.05). The lower limit of the 95% medical reference range of FC increased with the reduction in BW.@*CONCLUSIONS@#There is a significant increase in blood FC concentrations in very/extremely preterm infants and very/extremely low birth weight infants, and tend to decrease with the increases in GA and BW.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peso ao Nascer
/
Recém-Nascido Prematuro
/
Carnitina
/
Idade Gestacional
/
Recém-Nascido de muito Baixo Peso
/
Recém-Nascido de Peso Extremamente Baixo ao Nascer
Limite:
Feminino
/
Humanos
/
Lactente
/
Recém-Nascido
/
Gravidez
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2019
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS