Study on Immunophenotypes and Gene of Acute Lymphoblastic Leukemia--Review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1831-1835, 2018.
Article
em Zh
| WPRIM
| ID: wpr-774377
Biblioteca responsável:
WPRO
ABSTRACT
Transplantation-associated thrombotic microangiopathy (TA-TMA) is one of the fatal complications of hematopoietic stem cell transplantation(HSCT). The pathogenesis of TA-TMA has not been fully elucidated. The latest researches show that the abnormal activation of the complement system may lead to widespread endothelial injury which may play an important role in the pathogenesis of this disease. Incontrotable hypertension, proteinuria, increase of soluble C5b-9 concentration and early pericardial effusion are the risk factors of TA-TMA . In this review, the latest advances of pathogenesis, early diagnosis, treatment and other aspects of the progress of TA-TMA are summarized, so as to provide new ideas to early diagnosis and treatment in TA-TMA.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Doença Aguda
/
Imunofenotipagem
/
Transplante de Células-Tronco Hematopoéticas
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Microangiopatias Trombóticas
Tipo de estudo:
Risk_factors_studies
/
Screening_studies
Limite:
Humans
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Ano de publicação:
2018
Tipo de documento:
Article