Clinical value of blood lactate in predicting the prognosis of neonatal sepsis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 629-634, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-775133
ABSTRACT
OBJECTIVE@#To explore the clinical value of arterial blood lactate level in predicting the prognosis of neonatal sepsis.@*METHODS@#The clinical data of 301 cases of neonatal sepsis were collected, which mainly included biochemical indicators such as blood lactate on admission, C-reactive protein, and procalcitonin. ROC curves were plotted to evaluate the value of lactate level on admission in predicting the prognosis of neonatal sepsis.@*RESULTS@#The mortality rate was significantly higher for full-term infants in the severely-elevated lactate group than in the mildly-elevated lactate group and the normal lactate group (26.1% vs 3.1% and 0%; P<0.017). The poor prognosis group had a significantly increased lactate level on admission compared with the good prognosis group (6.5±5.1 mmol/L vs 3.6±1.7 mmol/L; P<0.05). The sensitivity and specificity of blood lactate level on admission (cutoff value 6.15 mmol/L) were 0.545 and 0.919 respectively, in predicting the prognosis of neonatal sepsis.@*CONCLUSIONS@#Early blood lactate level can be used as a biochemical parameter to predict the prognosis of neonatal sepsis as it has a high specificity but a low sensitivity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Proteína C-Reativa
/
Curva ROC
/
Sepse Neonatal
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
/
Lactente
/
Recém-Nascido
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2019
Tipo de documento:
Artigo
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