Pericyte Plasticity in the Brain / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 551-560, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-775461
ABSTRACT
Cerebral pericytes are perivascular cells that stabilize blood vessels. Little is known about the plasticity of pericytes in the adult brain in vivo. Recently, using state-of-the-art technologies, including two-photon microscopy in combination with sophisticated Cre/loxP in vivo tracing techniques, a novel role of pericytes was revealed in vascular remodeling in the adult brain. Strikingly, after pericyte ablation, neighboring pericytes expand their processes and prevent vascular dilatation. This new knowledge provides insights into pericyte plasticity in the adult brain.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Encéfalo
/
Encefalopatias
/
Capilares
/
Pericitos
/
Células Endoteliais
/
Retinopatia Diabética
/
Microambiente Celular
/
Remodelação Vascular
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Neuroscience Bulletin
Ano de publicação:
2019
Tipo de documento:
Artigo
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