Clinical Research on Alzheimer's Disease: Progress and Perspectives / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 1111-1118, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-775511
ABSTRACT
Alzheimer's disease (AD), the most common type of dementia, is becoming a major challenge for global health and social care. However, the current understanding of AD pathogenesis is limited, and no early diagnosis and disease-modifying therapy are currently available. During the past year, significant progress has been made in clinical research on the diagnosis, prevention, and treatment of AD. In this review, we summarize the latest achievements, including diagnostic biomarkers, polygenic hazard score, amyloid and tau PET imaging, clinical trials targeting amyloid-beta (Aβ), tau, and neurotransmitters, early intervention, and primary prevention and systemic intervention approaches, and provide novel perspectives for further efforts to understand and cure the disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Terapêutica
/
Sangue
/
Imageamento por Ressonância Magnética
/
Biomarcadores
/
Progressão da Doença
/
Pesquisa Biomédica
/
Diagnóstico
/
Doença de Alzheimer
/
Métodos
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Neuroscience Bulletin
Ano de publicação:
2018
Tipo de documento:
Artigo
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