Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 403-405, 2018.
Article
em En
| WPRIM
| ID: wpr-776653
Biblioteca responsável:
WPRO
ABSTRACT
Chronic kidney disease (CKD) is a major disease that threatens human health. With the progression of CKD, the risk of cardiovascular death increases, which is associated with the elevated levels of uremic toxins (UTs). Representative toxins such as indoxyl sulfate and p-cresyl sulfate are involed in CKD progression and cardiovascular events inseparable from the key role of endothelial dysfunction. The therapeutic strategies of UTs are aimed at signaling pathways that target the levels and damage of toxins in modern medicine. There is a certain relevance between toxins and "turbid toxin" in the theory of Chinese medicine (CM). CM treatments have been demonstrated to reduce the damage of gut-derived toxins to the heart, kidney and blood vessels. Modern medicine still lacks evidence-based therapies, so it is necessary to explore the treatments of CM.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Toxinas Biológicas
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Uremia
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Transdução de Sinais
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Tratamento Farmacológico
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Insuficiência Renal Crônica
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Mucosa Intestinal
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Medicina Tradicional Chinesa
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Metabolismo
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Chinese journal of integrative medicine
Ano de publicação:
2018
Tipo de documento:
Article