A brief history of artemisinin: Modes of action and mechanisms of resistance / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 331-336, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-776879
ABSTRACT
The cornerstone of antimalarial treatment, artemisinin, has reduced malaria associated morbidity and mortality worldwide. However, Plasmodium falciparum parasites with reduced sensitivity to artemisinin have emerged, and this threatens malaria control and elimination efforts. In this minireview, we describe the initial development of artemisinin as an antimalarial drug, its use both historically and currently, and our current understanding of its mode of action and the mechanisms by which malaria parasites achieve resistance.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2019
Tipo de documento:
Artigo
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