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Age and gender-associated metabolic characteristics of urinary stone patients / 동물의과학연구지
Journal of Biomedical Research ; : 172-176, 2015.
Artigo em Inglês | WPRIM | ID: wpr-77766
ABSTRACT
The aim of the present study was to investigate sex- and age-associated clinico-metabolic characteristics of urinary stone patients. A retrospective review was performed on data from 2,009 consecutive patients presenting with their first urinary stone episode between 2005 and 2013. Of the 2,009 patients, 1,426 (71.0%) satisfied the inclusion criteria and were enrolled in the study. Patients were grouped by age ( or =60 years old) and sex. The medical history and 24 hr urinary chemistry results of each patient were obtained. The mean age of the 165 (11.6%) patients aged 60 or over was 65.5 +/- 4.2 years. Body mass index was greater in elderly females than in younger females (p=0.031). After stratification by sex and age, lower urinary excretion of calcium and uric acid was a protective factor for both sexes among the elderly (p<0.05, each, respectively). Low urine pH was a common risk factor for both sexes among the elderly (p=0.013 in males, p=0.047 in females, respectively), whereas lower citrate excretion was a risk factor for only the elderly female group (p=0.004). With regard to urinary metabolic abnormalities, elderly females showed higher incidence of hypocitraturia compared to younger females (p=0.049). In conclusion, this study demonstrated the sex- and ageassociated clinico-metabolic characteristics of urinary stone patients. Thus, it is important to tailor metabolic evaluation and medical prevention therapies for patient according to sex and gender characteristics.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Ácido Úrico / Cálculos Urinários / Índice de Massa Corporal / Química / Cálcio / Incidência / Estudos Retrospectivos / Fatores de Risco / Ácido Cítrico / Urolitíase Tipo de estudo: Estudo de etiologia / Estudo de incidência / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Idoso / Feminino / Humanos / Masculino Idioma: Inglês Revista: Journal of Biomedical Research Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Ácido Úrico / Cálculos Urinários / Índice de Massa Corporal / Química / Cálcio / Incidência / Estudos Retrospectivos / Fatores de Risco / Ácido Cítrico / Urolitíase Tipo de estudo: Estudo de etiologia / Estudo de incidência / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Idoso / Feminino / Humanos / Masculino Idioma: Inglês Revista: Journal of Biomedical Research Ano de publicação: 2015 Tipo de documento: Artigo