Malignant Adenomyoepithelioma of the Breast and Responsiveness to Eribulin / 한국유방암학회지
Journal of Breast Cancer
;
: 400-403, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-77775
ABSTRACT
Adenomyoepithelioma (AME) of the breast is an uncommon tumor characterized by its dual differentiation into luminal cells and myoepithelial cells. In most cases these tumors have a benign clinical course, but distant metastases have been reported. We present the case of a 51-year-old woman diagnosed with malignant AME. The patient underwent a right modified radical mastectomy, and pathological examination confirmed the diagnosis of malignant AME. Ten months after the operation, multiple hepatic, pleural, and abdominal wall metastases were detected. A number of palliative chemotherapeutic agents were tried, including anthracycline and taxanes. However, the disease continued to progress, and superior vena cava syndrome developed as a result of direct tumor invasion. The patient received salvage eribulin monotherapy. After two cycles of this treatment, her clinical symptoms were ameliorated, and a computed tomography scan showed a partial response. Eribulin chemotherapy was thus effective in treating malignant AME in this case.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenobarbital
/
Síndrome da Veia Cava Superior
/
Mama
/
Mastectomia Radical Modificada
/
Parede Abdominal
/
Taxoides
/
Diagnóstico
/
Tratamento Farmacológico
/
Adenomioepitelioma
/
Metástase Neoplásica
Tipo de estudo:
Estudo diagnóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Breast Cancer
Ano de publicação:
2015
Tipo de documento:
Artigo
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