Advances in immunological treatment of autoimmune hepatitis / 临床肝胆病杂志

ABSTRACT

In recent years, autoimmune hepatitis (AIH) has attracted more and more attention due to its unique clinicopathological features. However, its incidence and clinical features remain unclear, and systematic and in-depth studies are still needed. This article reviews the epidemiology, etiology, pathogenesis, clinical features, and diagnosis and treatment of AIH and points out that clinical studies or animal models of AIH have proved the effects of TNF-α neutralizing antibody, rituximab, all-trans retinoic acid, and regulatory T cell transplantation in the treatment of AIH.