Application of tumor-associated antigens and their autoantibodies in early diagnosis of hepatocellular carcinoma / 临床肝胆病杂志

ABSTRACT

Early identification and diagnosis of hepatocellular carcinoma (HCC) is necessary for improving survival rates of HCC patients. Studies have shown that the abnormal proteins released by tumor cells, i.e., the autoantibodies stimulated by tumor-associated antigens (TAAs), can be detected before a clinical diagnosis of HCC is made, and therefore, such proteins may become the new markers for the early diagnosis of HCC. This article reviews the application of several new autoantibodies to tumor-associated antigens in the diagnosis of HCC and points out that these autoantibodies have promising prospects and clinical significance in the early diagnosis of HCC.