Establishment and application of a drug screening model for anti-prostate cancer agents targeting androgen receptor / 药学学报
Acta Pharmaceutica Sinica
;
(12): 287-2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-779167
ABSTRACT
Androgen receptor (AR) plays an important role in the maintenance of prostate function and development of prostate cancer. AR is the key target in the therapy of prostate cancer. In this study, a cell-based screening assay was established by dual-luciferase reporter system to analyze the activity of AR. In the screening assay, we detected the anti-prostate cancer activities of rhodiola root extract, wild kiwifruit root extract and tripterygium wilfordii root extract, which may provide a new strategy for the treatment of prostate cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2016
Tipo de documento:
Artigo
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