Inhibitors of aquaporin 1 and its role in tumor development and progression / 药学学报
Acta Pharmaceutica Sinica
; (12): 910-919, 2018.
Article
em Zh
| WPRIM
| ID: wpr-779951
Biblioteca responsável:
WPRO
ABSTRACT
Aquaporin 1 (AQP1), the first water channel protein discovered among the aquaporin family, is a hydrophobic transmembrane protein involved in transcellular water movement. Recent evidence shows that AQP1 plays a role in tumor cell proliferation and migration, angiogenesis and tumor development and progression, representing a potential therapeutic target. In this review, we discuss the structures, functions and inhibitors of AQP1, as well as the involvement of AQP1 in tumor development and progression.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2018
Tipo de documento:
Article