An assessment of the acetone extract from the leaves of Canarium odontophyllum (Miq.) for antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA)
Malaysian Journal of Microbiology
;
: 601-605, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-780456
ABSTRACT
Abstract@#Methicillin-resistant Staphylococcus aureus (MRSA) causes nosocomial and community infections and is a global health concern. This study evaluated the antibacterial activity of acetone extract from Canarium odontophyllum leaves against MRSA ATCC 33591 and Mu50 strains. The MIC/MBC ratio, determined using the broth micro dilution method, revealed the bacteriostatic effect of the extract against both strains. Time-kill assay against the Mu50 strain showed that the extract inhibited the growth of MRSA at low concentration but exhibited a concentration-dependent bacterial killing effect at 4× MIC. These findings confirm that an acetone extract from C. odontophyllum leaves inhibited growth of MRSA at low concentrations and could be utilised as an alternative anti-MRSA agent.
Texto completo:
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Malaysian Journal of Microbiology
Ano de publicação:
2018
Tipo de documento:
Artigo
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