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Clinical Features of Severely Constipated Children: Comparison of Infrequent Bowel Movement and Fecal Soiling Groups / 대한소아소화기영양학회지
Pediatric Gastroenterology, Hepatology & Nutrition ; : 26-34, 2020.
Artigo em Inglês | WPRIM | ID: wpr-782187
ABSTRACT
PURPOSE: To compare the clinical features, diagnostic findings, and medications of children with infrequent bowel movements or fecal soiling.

METHODS:

This study enrolled 333 children (189 male; age range, 1 month to 18 years) diagnosed with functional constipation by Rome III or IV criteria. We classified them into 3 groups (infrequent bowel movement without fecal soiling [G3-a], infrequent bowel movement with fecal soiling [G3-b], and fecal soiling only [G3-c]) and into 2 subgroups of fecal soiling (G2-b) or not (G2-a). Retrospective data on clinical characteristics, colon transit time (CTT) test results, and medications were collected. The Wilcoxon rank-sum test, Kruskal-Wallis test, Chi-square test, and Fisher's exact test were used for the statistical analysis.

RESULTS:

The median age (months) and interquartile range (IQR) was 33 (45) in G3-a, 54 (40) in G3-b, and 73 (48) in G3-c (p < 0.0001). G3-c had the latest onset (median, 18; IQR, 18; p=0.0219) and longest symptom duration (24 [24], p=0.0148). PEG 4000 was used in 60.6% (G3-a), 96.8% (G3-b), and 83.2% (G3-c) of patients (p < 0.0001). The median age (months) and IQR were 33.0 (45.0) in G2-a and 63.5 (52.5) in G2-b (p < 0.0001). G2-b had later onset (median, 12; IQR, 19.5; p=0.0062) and longer symptom duration than G2-a (24 [12], p=0.0070). PEG 4000 was used in 60.6% (G2-a) and 88.3% (G2-b) of children (p < 0.0001). No statistically significant intergroup differences were seen in maintenance laxative dose, CTT, or CTT type.

CONCLUSION:

Infrequent bowel movement and fecal soiling represent the advanced stage of chronic functional constipation.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Polietilenoglicóis / Solo / Estudos Retrospectivos / Colo / Constipação Intestinal / Defecação / Incontinência Fecal Tipo de estudo: Estudo observacional Limite: Criança / Humanos / Masculino Idioma: Inglês Revista: Pediatric Gastroenterology, Hepatology & Nutrition Ano de publicação: 2020 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Polietilenoglicóis / Solo / Estudos Retrospectivos / Colo / Constipação Intestinal / Defecação / Incontinência Fecal Tipo de estudo: Estudo observacional Limite: Criança / Humanos / Masculino Idioma: Inglês Revista: Pediatric Gastroenterology, Hepatology & Nutrition Ano de publicação: 2020 Tipo de documento: Artigo