Comparison of Serum Creatinine Measurements among Roche Modular D, Cobas 8000 c702, and Beckman Coulter AU5800, by Jaffe and Enzymatic Methods

ABSTRACT

0.99, slope 0.965 and 0.955). When Modular D and Cobas 8000c 702 were compared, the slope and y-intercept were 0.9928 (95% confidence interval [CI] 0.9802 to 1.000) and -0.0156 (95% CI −0.0200 to −0.0054), respectively. The slope and y-intercept were 0.9811 (95% CI 0.9570 to 0.9951) and -0.0484 (95% CI −0.0638 to −0.0297) when Modular D and Au5800 were compared. Serum Cr measured by Cobas 8000 c702 and AU5800 using the Jaffe method were 3.2% and 6.9% lower than the values measured by Modular D, respectively. Both Modular D and Cobas 8000 c702 showed acceptable accuracies.CONCLUSIONS: Serum Cr measurements using Cobas 8000 c702 and AU5800 were comparable to those measured by Modular D, and showed satisfactory precision and linearity; thus, these techniques could be useful for clinical laboratories.