Making In Vivo Model To Study About Human Oral Cancer (I)
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons
;
: 300-310, 1997.
Artigo
em Inglês
| WPRIM
| ID: wpr-784086
ABSTRACT
human oral squamous cell cancer, we brought up BALB/C nude mice in specially designed housing system, and maintained some kind of human oral squamous cancer cell lines ; KB, SCC-4, SCC-9, SCC-15, SCC-25. Various concentration of cancer cells were inoculated subcutaneously into flank area of nude mice. We observed each nude mouse more than 5 weeks after tumor inoculation. We appraised the results, measured the tumor size, and calculated the growing tumor volumes after tumor inoculation according to cancer cell line and concentration of cancer cells in media. Some cancer cell lines were rapidly growing in nude mice, but some cancer cell line couldn't grow in nude mice and resorbed completely. And in some cancer cell line, some nude mice showed continuously growing tumor, but other didn't show any tumor growing. And as a new try, we implanted specially designed caps on the back of nude mice, and cancer cell lines were brought into the caps with media. We removed the cap after 1 week, and observed over 4 weeks, The shape and size of growing tumor were observed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Bucais
/
Linhagem Celular
/
Neoplasias de Células Escamosas
/
Habitação
/
Camundongos Nus
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons
Ano de publicação:
1997
Tipo de documento:
Artigo
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