An experimental study on the effect of LASER on soft tissue healing

ABSTRACT

OBJECTIVES: This study is aimed to compare the wound healing processes between conventional scapel wound and Er,CrYSGG (Erbium,Chromium, Yttrium, Scandium, Gallium, Garnet) laser wound using experimental animals.EXPERIMENTAL DESIGN: Two types of wounds were made by linear and round incisions using scalpel and Er,CrYSGG laser, respectively, on the thigh of Sprague-Dawley rats. Sprague-Dawley rats were serially sacrified as follows post operative 12, 24, 48 hours, and 3, 7, 14 days. The skin wounds were grossly and microscopically analyzed during the healing period.RESULT: The Er,CrYSGG laser incision showed better wound healing for the linear incision experiment than the scapel incision. Whereas the scapel incision showed better wound healing for the round incision experiment than the Er,CrYSGG linear incision. As the Er,CrYSGG laser damage in the round incision experiment could be much increased compared with the round incision by scapel. So, the round incisions by the Er,CrYSGG laser were resulted in the poor wound healing compared with those by the scapel.CONCLUSION: The Er,CrYSGG laser is more favorable for the fast linear incision, while the scapel is more favorable for the modified round incision.