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Association between cadmium exposure and hearing impairment: a population-based study in Korean adults / 영남의대학술지
Yeungnam University Journal of Medicine ; : 141-147, 2019.
Artigo em Inglês | WPRIM | ID: wpr-785308
ABSTRACT

BACKGROUND:

The present study aimed to evaluate the clinical association between cadmium exposure and hearing impairment among the Korean population.

METHODS:

This retrospective cross-sectional study used the data obtained from the Korean National Health and Nutrition Examination Survey were used for our study. Finally, 3,228 participants were included in our study, which were then divided into quartiles based on their blood cadmium levels first quartile (1Q), second quartile (2Q), third quartile (3Q), and fourth quartile (4Q) groups. The hearing thresholds were measured using an automatic audiometer at 0.5, 1, 2, 3, 4, and 6 kHz. Hearing loss (HL) was defined as >25 dB average hearing threshold (AHT).

RESULTS:

All the groups had 807 participants each. The area under the receiver operating characteristic curves of cadmium level for HL were 0.634 (95% confidence interval [CI], 0.621–0.646). The participants in the 4Q group had higher Low/Mid-Freq, High-Freq, and AHT values than those in the other groups in the multivariate analysis after adjusting for confounding factors. The logistic regression showed that the OR for HL per 1 µg/L increase in cadmium was 1.25 (95% CI, 1.09–1.44; p=0.002) on the multivariate analysis. Moreover, the multivariate logistic regression analyses revealed that the participants in the 4Q group exhibited a 1.59-, 1.38-, and 1.41-fold higher odds for HL than those in the 1Q, 2Q, and 3Q groups, respectively.

CONCLUSION:

High cadmium level quartile was associated with increased hearing thresholds and HL among the Korean adult population.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Cádmio / Modelos Logísticos / Inquéritos Nutricionais / Estudos Transversais / Análise Multivariada / Estudos Retrospectivos / Curva ROC / Metais Pesados / Audição / Perda Auditiva Tipo de estudo: Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco Limite: Adulto / Humanos Idioma: Inglês Revista: Yeungnam University Journal of Medicine Ano de publicação: 2019 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Cádmio / Modelos Logísticos / Inquéritos Nutricionais / Estudos Transversais / Análise Multivariada / Estudos Retrospectivos / Curva ROC / Metais Pesados / Audição / Perda Auditiva Tipo de estudo: Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco Limite: Adulto / Humanos Idioma: Inglês Revista: Yeungnam University Journal of Medicine Ano de publicação: 2019 Tipo de documento: Artigo