Concurrent Anti-glomerular Basement Membrane Nephritis and IgA Nephropathy
Journal of Pathology and Translational Medicine
;
: 399-402, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-786124
ABSTRACT
Anti–glomerular basement membrane (GBM) nephritis is characterized by circulating anti-GBM antibodies and crescentic glomerulonephritis (GN) with deposition of IgG along the GBM. In a limited number of cases, glomerular immune complexes have been identified in anti-GBM nephritis. A 38-year-old female presented azotemia, hematuria, and proteinuria without any pulmonary symptoms. A renal biopsy showed crescentic GN with linear IgG deposition along the GBM and mesangial IgA deposition. The patient was diagnosed as concurrent anti-GBM nephritis and IgA nephropathy. Therapies with pulse methylprednisolone and cyclophosphamide administration were effective. Concurrent cases of both anti-GBM nephritis and IgA nephropathy are rare among cases of anti-GBM diseases with deposition of immune complexes. This rare case of concurrent anti-GBM nephritis and IgA nephropathy with literature review is noteworthy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Proteinúria
/
Membrana Basal
/
Biópsia
/
Imunoglobulina A
/
Imunoglobulina G
/
Metilprednisolona
/
Doença Antimembrana Basal Glomerular
/
Ciclofosfamida
/
Azotemia
/
Glomerulonefrite
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Pathology and Translational Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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