Effect of ME Collimator Characteristic, Energy Window Width, and Reconstruction Algorithm Selection on Imaging Performance of Yttrium-90: Simulation Study / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 414-422, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-786499
ABSTRACT
PURPOSE:
The treatment efficiency of ⁹⁰Y and providing reliable estimates of activity are evaluated by SPECT imaging of bremsstrahlung radiation released during beta therapy. In this technique, the resulting spectrum from ⁹⁰Y is very complex and continuous, which creates difficulties on the imaging protocol. Moreover, collimator geometry has an impressive effect on the spatial resolution, system sensitivity, image contrast, and the signal-to-noise ratio (SNR), which should be optimized.METHODS:
We evaluated the effect of energy window width, reconstruction algorithms, and different geometries of a medium-energy (ME) parallel-hole collimator on the image contrast and SNR of ⁹⁰Y SPECT images. The Siemens E.Cam gamma camera equipped with a ME collimator and a digital Jaszczak phantom were simulated by SIMIND Monte Carlo program to generate the ⁹⁰Y bremsstrahlung SPECT images.RESULTS:
Our results showed that optimal image quality can be acquired by the reconstruction algorithm of OS-EM in the energy window width of 60 to 400 keV for ⁹⁰Y bremsstrahlung SPECT imaging. Furthermore, the optimal values of the hole diameter and hole length of a ME collimator were obtained 0.235 and 4.4 cm, respectively.CONCLUSIONS:
The acquired optimal ME collimator and energy window along with using a suitable reconstruction algorithm lead to improved contrast and SNR of ⁹⁰Y bremsstrahlung images of hot spheres of the digital Jaszczak phantom. This can improve the accuracy and precision of the ⁹⁰Y activity distribution estimation after radioembolization in targeted radionuclide therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Câmaras gama
/
Tomografia Computadorizada de Emissão de Fóton Único
/
Razão Sinal-Ruído
Tipo de estudo:
Guia de Prática Clínica
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Korean Journal of Nuclear Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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