Changing Susceptibility of Staphylococcus aureus in Children with Skin and Soft Tissue Infections: a Single Center Experience from 2010 to 2018
Pediatric Infection & Vaccine
;
: 140-147, 2019.
Artigo
em Coreano
| WPRIM
| ID: wpr-786533
ABSTRACT
PURPOSE:
Staphylococcus aureus is a major cause of skin and soft tissue infections (SSTIs). This study aimed to determine the temporal trends in antibiotic susceptibility of S. aureus in SSTI patients aged <19 years.METHODS:
This retrospective observational study was conducted in pediatric patients with SSTI caused by community-associated S. aureus. Microbiologic and demographic data were collected, and the trends of antibiotic susceptibility results were evaluated.RESULTS:
From January 2010 to December 2018, a total of 807 S. aureus isolates were included. An overall increase in susceptibility of isolates to oxacillin was noted (P<0.001), with 75.0% of isolates being oxacillin-susceptible in 2018. S. aureus remained highly susceptible to trimethoprim/sulfamethoxazole and tetracycline, with 97.6% and 95.2% isolate susceptibility in 2018, respectively. Isolates from younger children aged 1 to 5 years had a significantly lower rate of susceptibility to oxacillin than older children aged 6 to 18 years (53.4% vs. 75.0%, P<0.001).CONCLUSIONS:
The proportion of methicillin-resistant S. aureus isolates appears to decrease in pediatric patients with community-associated SSTI caused by S. aureus. Clinicians should be aware of regional susceptibility patterns when choosing empirical regimens.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxacilina
/
Pele
/
Staphylococcus
/
Staphylococcus aureus
/
Tetraciclina
/
Infecções Cutâneas Estafilocócicas
/
Estudos Retrospectivos
/
Resistência a Meticilina
/
Infecções dos Tecidos Moles
/
Estudo Observacional
Tipo de estudo:
Estudo observacional
Limite:
Criança
/
Humanos
Idioma:
Coreano
Revista:
Pediatric Infection & Vaccine
Ano de publicação:
2019
Tipo de documento:
Artigo
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