Vascular Dementia / 전남의대학술지
Chonnam Medical Journal
;
: 66-71, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-788207
ABSTRACT
Cerebrovascular disease is the second leading cause of cognitive impairment in the elderly, either alone or in combination with Alzheimer's disease (AD). Vascular dementia (VaD) is heterogeneous in terms of both clinical phenotype and pathogenetic mechanisms. It may result from multiple cortical infarctions due to cerebral large vessel pathologies or to subcortical ischemic changes such as leukoaraiosis or lacunar infarction due to cerebral small artery disease. Clinical symptoms and signs vary depending on the location and size of the stroke lesion, and no single neuropsychological profile characteristic of VaD has been defined, although dysexecutive function is common. A slightly higher mortality rate and slower progression are reported in VaD compared with AD. VaD is potentially preventable by rigorous identification and treatment of cardiovascular disease risk factors, and modest symptomatic improvement with cholinesterase inhibitors has been reported.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenótipo
/
Artérias
/
Doenças Cardiovasculares
/
Demência Vascular
/
Transtornos Cerebrovasculares
/
Inibidores da Colinesterase
/
Fatores de Risco
/
Acidente Vascular Cerebral
/
Leucoaraiose
/
Função Executiva
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Chonnam Medical Journal
Ano de publicação:
2011
Tipo de documento:
Artigo
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