A Case of Central Retinal Vein Occlusion by Protein C Deficiency / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
;
: 54-57, 2011.
Artigo
em Coreano
| WPRIM
| ID: wpr-788429
ABSTRACT
Protein C (PC) is a vitamin K-dependent plasma protein synthesized as a zymogen by liver. It's active form has an anti-thrombotic activity by cleaving the coagulation factor Va and VIIIa. During the last few years, a large number of cases with protein C deficiency (PCD) which contain variable mutations have been documented. Those with hereditary protein C deficiency tend to have an increased risk of thromboembolism. Hypertension, diabetes, hyperlipidemia and glaucoma are the main underlying diseases of the retinal vein occlusion (RVO). Rarely, thrombophilia (antithrombin III, protein S, protein C deficiency) results in the RVO which usually occurs after adolescent period. We recently experienced a case of central retinal vein occlusion by a PCD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plasma
/
Veia Retiniana
/
Tromboembolia
/
Vitaminas
/
Oclusão da Veia Retiniana
/
Proteína C
/
Fator Va
/
Glaucoma
/
Proteína S
/
Trombofilia
Limite:
Adolescente
/
Humanos
Idioma:
Coreano
Revista:
Clinical Pediatric Hematology-Oncology
Ano de publicação:
2011
Tipo de documento:
Artigo
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