Variability of Platelet Reactivity on Antiplatelet Therapy in Neurointervention Procedure
Journal of Korean Neurosurgical Society
;
: 3-9, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-788754
ABSTRACT
As more intracranial aneurysms and other cerebrovascular pathologies are treated with neurointervention procedure, thromboembolic events that frequently lead to serious neurological deficit or fatal outcomes are increasing. In order to prevent the thromboembolic events, antiplatelet therapy is used in most procedures including coil embolization, stenting, and flow diversion. However, because of variable individual pharmacodynamics responses to antiplatelet drugs, especially clopidogrel, it is difficult for clinicians to select the adequate antiplatelet regimen and its optimal dose. This article reviews the neurointervention literature related to antiplatelet therapy and suggests a strategy for tailoring antiplatelet therapy in individual patients undergoing neurointervention based on the results of platelet function testing.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Testes de Função Plaquetária
/
Plaquetas
/
Inibidores da Agregação Plaquetária
/
Stents
/
Aneurisma Intracraniano
/
Aspirina
/
Evolução Fatal
/
Embolização Terapêutica
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Korean Neurosurgical Society
Ano de publicação:
2019
Tipo de documento:
Artigo
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