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Inflammasome and diseases of central nervous system / 药学实践杂志
Journal of Pharmaceutical Practice ; (6): 12-15, 2016.
Artigo em Chinês | WPRIM | ID: wpr-790546
ABSTRACT
Inflammasome is the body of protein complex which is able to identify different stimulation signals and can in‐duce immune and inflammatory responses when it is activated .NLRP3 inflammasome has been extensively studied in the central nervous system .Microglia ,perivascular macrophages and meningeal macrophages express inflammasomes .The occurrence and development of acute brain infection ,aseptic acute brain injury ,Parkinson disease and Alzheimer disease are closely related to inflammasomes .Based on mechanisms exploration of the inflammasome′s role in the central nervous system disorders ,its tar‐get drug research and development will be greatly addressed in the future .

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of Pharmaceutical Practice Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of Pharmaceutical Practice Ano de publicação: 2016 Tipo de documento: Artigo