The mechanisms of inflammation and apoptosis in myocardial infarction / 药学实践杂志

ABSTRACT

The inflammation and apoptosis were vital important in the progress and recovery in myocardial infarction. Apoptosis was regulated by inflammation though TNF-α,CHOP,IL-10 andα7nAChR signal pathways and influenced the se-verity of the inflammation via feedback regulation.Inflammation and apoptosis affected myocardial infarction size and cardiac function recovery together.Inhibition of inflammation,reducing apoptosis had been proved to be the important parts in preven-tion of ventricular remodeling and regulating cardiac dysfunction after myocardial infarction,which had broad prospects.