Progress of tamsulosin hydrochloride sustained-release preparation / 药学实践杂志

ABSTRACT

Tamsulosin hydrochloride is widely used for the treatment of lower urinary tract symptoms of benign prostatic hyperplasia ,requiring long-term medication .It reduces adverse reactions of hypotension and dizziness by rapid absorption from oral intake .The sustained-release (SR) formulation is recommended for clinical application .Currently in domestic and foreign market,SRproductsmainlyincludeSRcapsulesandSRtablets,likeFlomaxR○ andHarnalR○ .Thedomesticmarketmainlyuses the originally developed Harnal R○ SR capsules .In accordance with the drug′s potential market ,more and more SR studies have been done .This article reviews the research progress of tamsulosin hydrochloride sustained-release preparation .