Meta-analysis on renal toxicity of vancomycin given by continuous infusion vs in-termittent infusion / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 136-139,146, 2018.
Article
em Zh
| WPRIM
| ID: wpr-790851
Biblioteca responsável:
WPRO
ABSTRACT
Objective To compare the renal toxicity of vancomycin with continuous infusion vs intermittent infusion. Methods The databases of EMBASE,PUBMED,the Cochrane Register of Controlled Trials,CBM,CNKI and WanFang were searched.The Cochrane Revman5.2 software was used for Meta-analysis.Results Two RCTs and eight observational studies were included in the systematic literature search with total of 1 764 patients.1 037 patients received vancomycin with continuous infusion while 727 patients with intermittent infusion.The Meta-analysis indicated that there was no significant difference in renal toxicity between continuous infusion group and intermittent infusion group(P>0.05).Conclusion Vanco-mycin continuous infusion cannot effectively reduce the incidence of renal toxicity.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Observational_studies
/
Systematic_reviews
Idioma:
Zh
Revista:
Journal of Pharmaceutical Practice
Ano de publicação:
2018
Tipo de documento:
Article