Advances in immunomodulatory effects of catecholamines in critical illness / 中华危重病急救医学
Chinese Critical Care Medicine
;
(12): 1295-1298, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-791070
ABSTRACT
Immune disorders are common in critically ill patients. Catecholamines play a crucial role in theimmune regulation and modulation. Immune cells can synthesize catecholamines and express adrenergic receptors. Catecholamine has a wide-ranging regulatory effect on innate immunity such as neutrophils, monocyte macrophages, dendritic cells, natural killer cells, and lymphocyte-mediated acquired immunity. Catecholamines exert different immunomodulatory effects by binding to α receptors, β receptors, and dopamine receptor subtypes on immune cells. In-depth study of the effect and mechanism of catecholamine on immune function in critically ill patients will provide new ideas for the prevention and treatment of immune dysfunction in critical illness.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Critical Care Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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