Comprehensive treatment in stroke unit can improve the cognitive function and the life quality of stroke sur-vivors with vascular cognitive impairment as well as the mental state of their caregivers / 中华物理医学与康复杂志

ABSTRACT

Objective To study the effect of comprehensive treatment in stroke unit on the cognition and life quality of patients with vascular cognitive impairment ( VCI) and also its effects on the mental state of their caregiv-ers. Methods Ninety-three persons with VCI were randomly divided into a control group ( n=44) and a compre-hensive treatment group ( n=49) after being admitted into the stroke unit. Both groups took routine basic drugs ( such as anti-platelet drugs, lipid lowering drugs, anti-hypertension drugs, huperzine-A tablets and Nicergoline tablets). The treatment group was additionally provided with limb movement rehabilitation training, social practice, cognitive training and health education. During the treatment, the treatment group's caregivers were also given health education about VCI and stroke, systematic rehabilitation knowledge and skills training and appropriate anti-depressant and anx-iety medication if need. Before the treatment, as well as 3 and 6 months after the treatment, the patients of both groups were evaluated using the mini-mental state examination ( MMSE ) , the Montreal cognitive assessment ( MoCA) , their ability in the activities of daily living ( ADL) was rated and Spitzer quality of life ( QLI) values were assigned. The caregivers were evaluated using the Hamilton depression scale (HAMD) and the Hamilton anxiety scale ( HAMA) . Results After 3 and 6 months of treatment, the average MMSE, MoCA, ADL and QLI scores of the treatment group had improved significantly and were then significantly better than those of the control group at the same time points. The average HAMD score of the treatment group was also significantly better. Conclusion Com-prehensive stroke unit therapy can improve the cognition and life quality of patients with vascular cognitive impair-ment. It can also improve the mental state of their caregivers.